• Doping Polycyclic Aromatics with Boron for Superior Performance in Materials Science and Catalysis
  • Doping Polycyclic Aromatics with Boron for Superior Performance in Materials Science and Catalysis

    Delightful deficiency: Because of its vacant p orbital, an incorporated boron atom can imprint peculiar optoelectronic properties on polycyclic aromatic hydrocarbons (PAHs). Recently, synthetic strategies have been developed to provide access to B-PAHs that are specifically tailored to applications as catalysts for the activation of small molecules or as luminophores and charge carriers in optoelectronic devices.

    [Focus Review]
    Esther von Grotthuss, Alexandra John, Thomas Kaese, Matthias Wagner
    Asian J. Org. Chem., November 24, 2017, https://doi.org/10.1002/ajoc.201700495 Read article



  • Horseradish Peroxidase Catalyzed Hydrogelation for Biomedical, Biopharmaceutical, and Biofabrication Applications
  • Horseradish Peroxidase Catalyzed Hydrogelation for Biomedical, Biopharmaceutical, and Biofabrication Applications

    Gelling together: Horseradish peroxidase (HRP)-catalyzed hydrogelation has attracted much attention owing to ease of handling, biocompatibility, and processability. This review summarizes recent developments in the use of HRP-mediated hydrogelation toward biomedical, biopharmaceutical, and biofabrication applications (see figure).

    [Focus Review]
    Shinji Sakai, Masaki Nakahata
    Chem. Asian J., November 23, 2017, https://doi.org/10.1002/asia.201701364 Read article



  • Enantioselective Synthesis of Chromenes via a Palladium-Catalyzed Asymmetric Redox-Relay Heck Reaction
  • Enantioselective Synthesis of Chromenes via a Palladium‐Catalyzed Asymmetric Redox‐Relay Heck Reaction

    Relay race: A palladium-catalyzed asymmetric redox-relay Heck reaction of 4H-chromenes and arylboronic acids has been successfully developed. The reaction proceeded in moderate to good yields with good to high enantioselectivities. One resulting product is an advanced intermediate of bio-active compound BW683C.

    [Communication]
    Ze-Zhen Jiang, Ang Gao, Hao Li, Di Chen, Chang-Hua Ding, Bin Xu, Xue-Long Hou
    Chem. Asian J., November 23, 2017, https://doi.org/10.1002/asia.201701504 Read article



  • Quantitative Analysis of the Self-Assembly Process of a Pd12L24 Coordination Sphere
  • Quantitative Analysis of the Self‐Assembly Process of a Pd12L24 Coordination Sphere

    Get results ASAP? NMR-based QASAP (quantitative analysis of self-assembly process) revealed that a Pd12L24 sphere was self-assembled through two pathways: intra-/intermolecular reaction of the intermediates not observed by 1H NMR (Int) (Path A) and the production of kinetic traps of PdnL2n complexes, which were converted into the sphere through the reaction with Int (Path  B).

    [Full Paper]
    Shumpei Kai, Taro Shigeta, Tatsuo Kojima, Shuichi Hiraoka
    Chem. Asian J., November 23, 2017, https://doi.org/10.1002/asia.201701351 Read article



  • Design and Synthesis of Porous Coordination Polymers with Expanded One-Dimensional Channels and Strongly Lewis-Acidic Sites
  • Design and Synthesis of Porous Coordination Polymers with Expanded One‐Dimensional Channels and Strongly Lewis‐Acidic Sites

    Porous coordination polymers (PCPs) consisting of LaIII cations and thiophene-based tritopic organic linkers are synthesized and characterized. By using thiophene-bridged benzenecarboxylates and benzene-bridged thiophenecarboxylates, both linkers afford the same framework topology with one-dimensional hexagonal channels, whereas the thermal and chemical stability of them differ significantly from each other. Both La-PCPs show high activity in the Lewis-acid-catalyzed cyanosilylation.

    [Full Paper]
    Takashi Kajiwara, Hideyuki Higashimura, Masakazu Higuchi, Susumu Kitagawa
    ChemNanoMat, November 23, 2017, https://doi.org/10.1002/cnma.201700256 Read article



  • Crystal and NMR Structures of a Peptidomimetic β-Turn That Provides Facile Synthesis of 13-Membered Cyclic Tetrapeptides
  • Crystal and NMR Structures of a Peptidomimetic β‐Turn That Provides Facile Synthesis of 13‐Membered Cyclic Tetrapeptides

    Taking a turn for the better: A new β-turn structure of the tetrapeptide H2N-d-Leu-d-Phe-2-Abz-d-Ala-COOH was revealed by using X-ray crystallography and 2D 1H NMR studies. This compound and its NMe-d-Phe derivative provide facile cyclization for the synthesis of cyclic tetrapeptides, which display highly planar ring structures as evidenced by NMR spectroscopy and X-ray crystallography.

    [Full Paper]
    Alan J. Cameron, Christopher J. Squire, Patrick J. B. Edwards, Elena Harjes, Vijayalekshmi Sarojini
    Chem. Asian J., November 22, 2017, https://doi.org/10.1002/asia.201701422 Read article



  • Preparation and Thermal Properties of Polycarbonates/esters Catalyzed by Using Dinuclear Salph-Al from Ring-Opening Polymerization of Epoxide Monomers
  • Preparation and Thermal Properties of Polycarbonates/esters Catalyzed by Using Dinuclear Salph‐Al from Ring‐Opening Polymerization of Epoxide Monomers

    Dinuclear Salph-Al: A dinuclear Salph-Al complex showed high selectivity toward carbonate linkages in cyclohexene oxide/CO2 copolymerization. For epoxide/phthalic anhydride polymerization, the epoxide participated in the reaction proportionally and the obtained polyester had a controllable glass transition temperature (Tg; see figure).

    [Full Paper]
    Yanchuan Zhou, Ranlong Duan, Xiang Li, Xuan Pang, Xianhong Wang, Xuesi Chen
    Chem. Asian J., November 22, 2017, https://doi.org/10.1002/asia.201701048 Read article



  • Efficient Solution- and Solid-State Fluorescence for a Series of 7-Diethylaminocoumarin Amide Compounds
  • Efficient Solution‐ and Solid‐State Fluorescence for a Series of 7‐Diethylaminocoumarin Amide Compounds

    7-Heaven: A series of 7-diethylaminocoumarin amides that exhibited strong fluorescence in THF, high-viscosity glycerol solution, and the solid state (powder) have been synthesized. The phenyl amide displayed enhanced fluorescence in the solid state relative to that in THF. The high-viscosity glycerol and solid states may restrict the rotation of the 7-diethylamino group, thereby leading to nonradiative deactivation and fluorescence enhancement.

    [Full Paper]
    Yatong Sun, Yunhui Sun, Songfang Zhao, Duxia Cao, Ruifang Guan, Zhiqiang Liu, Xueying Yu, Xun Zhao
    Asian J. Org. Chem., November 22, 2017, https://doi.org/10.1002/ajoc.201700555 Read article



  • Synthesis of Chiral Acyclic Pyrimidine Nucleosides with a Sulfur-Containing Side Chain via Enantioselective Tandem Conjugate Addition/Protonation
  • Synthesis of Chiral Acyclic Pyrimidine Nucleosides with a Sulfur‐Containing Side Chain via Enantioselective Tandem Conjugate Addition/Protonation

    AdPro: A direct route to chiral pyrimidine acyclic nucleoside analogues with a sulfur-containing side chain has been reported via enantioselective tandem conjugated addition/protonation reactions of thioacetic acid to α-pyrimidine substituted acrylates. In the presence of a quinine-derived thiourea catalyst, diverse chiral sulfur-containing pyrimidine acyclic nucleoside analogues were formed in excellent yields (95–99 %) and moderate to excellent enantioselectivities (up to 99 % ee).

    [Communication]
    Jian-Ping Li, Hao-Ran Tuo, Ming-Sheng Xie, Bo Kang, Gui-Rong Qu, Hai-Ming Guo
    Asian J. Org. Chem., November 22, 2017, https://doi.org/10.1002/ajoc.201700533 Read article



  • A Templateless Electropolymerization Approach to Nanorings Using Substituted 3,4-Naphthalenedioxythiophene (NaPhDOT) Monomers
  • A Templateless Electropolymerization Approach to Nanorings Using Substituted 3,4‐Naphthalenedioxythiophene (NaPhDOT) Monomers

    Homogeneous arrays of nanorings are obtained using a templateless electropolymerization of substituted NaphDOT. Exceptional results are obtained with a naphthalene substituent.

    [Full Paper]
    André Gbilimou, Thierry Darmanin, Guilhem Godeau, Frédéric Guittard
    ChemNanoMat, November 21, 2017, https://doi.org/10.1002/cnma.201700269 Read article



  • Controllable Activation of Pd-G3 Palladacycle Precatalyst in the Presence of Thiosugars: Rapid Access to 1-Aminobiphenyl Thioglycoside Atropoisomers at Room Temperature
  • Controllable Activation of Pd‐G3 Palladacycle Precatalyst in the Presence of Thiosugars: Rapid Access to 1‐Aminobiphenyl Thioglycoside Atropoisomers at Room Temperature

    Pour some thiosugar on me: Activation of XantPhos Pd-G3 precatalyst with thiosugars and thiols under mild and operationally simple reaction conditions is reported. A series of 1-aminobiphenyl thioglycosides has been synthesized in very high yields.

    [Communication]
    Riyadh Ahmed Atto AL-Shuaeeb, Camille Dejean, Mouâd Alami, Samir Messaoudi
    Chem. Asian J., November 21, 2017, https://doi.org/10.1002/asia.201701415 Read article



  • Recent Developments and Perspectives in the Zinc-Catalysed Michael Addition
  • Recent Developments and Perspectives in the Zinc‐Catalysed Michael Addition

    Going greener: Zinc catalysis affords the Michael addition excellent reactivity and selectivity, and a broad substrate scope and mild reaction conditions have established this carbon–carbon and carbon–heteroatom bond-forming reaction as one of the most useful. This Focus Review examines what has been achieved since 2001 with the use of zinc, sometimes in conjunction with a ligand, in this important and increasingly green area of organic synthesis.

    [Focus Review]
    K. R. Rohit, S. M. Ujwaldev, K. Keerthi Krishnan, Gopinathan Anilkumar
    Asian J. Org. Chem., November 21, 2017, https://doi.org/10.1002/ajoc.201700491 Read article



Powered by Web RSS