• Stereoselective Traceless Borylation–Allenation of Propargylic Epoxides: Dual Role of the Copper Catalyst
  • Stereoselective Traceless Borylation–Allenation of Propargylic Epoxides: Dual Role of the Copper Catalyst

    Dual player: In this report, chiral α-allenols are prepared with high diastereocontrol through an unprecedented and spontaneous β-oxygen elimination of an α-epoxy vinyl boronate. Stoichiometric experiments and DFT calculations support a dual role of the copper catalyst, which orchestrates the hydroboration and the syn-elimination step.

    [Communication]
    Carlos Jarava-Barrera, Alejandro Parra, Laura Amenós, Ana Arroyo, Mariola Tortosa
    Chem. Eur. J., November 24, 2017, https://doi.org/10.1002/chem.201705019 Read article



  • Interfacial Chemistry-Modified QD-Coupled CdTe Solid Nanowire and Its Hybrid with Graphene Quantum Dots for Enhanced Photocurrent Properties
  • Interfacial Chemistry‐Modified QD‐Coupled CdTe Solid Nanowire and Its Hybrid with Graphene Quantum Dots for Enhanced Photocurrent Properties

    The CdTe quantum dots initially come closer through the formation of C−O-C bonds between the MPA molecules capped adjacent quantum dots. With prolonging the reaction further, the closer quantum dots fuse to form a solid CdTe wire like structure. In the case of graphene hybrids, the C−O-C bond formation takes place between the carboxyl group of graphene quantum dots and the CdTe nanowire. While formation of CdTe solid nanowire produced a high photocurrent value, its hybridization enhanced its photocurrent further.

    [Full Paper]
    Sellan Premkumar, Devaraj Nataraj, Ganapathi Bharathi, Oleg Yu Khyzhun, T. Daniel Thangadurai
    ChemistrySelect, November 24, 2017, https://doi.org/10.1002/slct.201702352 Read article



  • β-Cyclodextrin-Monosulphonic Acid Catalyzed Efficient Synthesis of 1-Amidoalkyl-2-naphthols
  • β‐Cyclodextrin‐Monosulphonic Acid Catalyzed Efficient Synthesis of 1‐Amidoalkyl‐2‐naphthols

    An efficient and rapid approach for the synthesis of 1-amidoalkyl-2-naphthols catalyzed by β-cyclodextrin-monosulphonic acid is described. The catalyst prepared easily in a single step from β-cyclodextrin. Totally 29 compounds prepared using this catalyst indicating the broad substrate scope of the present work. The signficant advantages of this method are easy preparation of the catalyst, short reaction time, high yields, simple workup and reusability upto five times.

    [Full Paper]
    Natarajan Madankumar, Kasi Pitchumani
    ChemistrySelect, November 24, 2017, https://doi.org/10.1002/slct.201702038 Read article



  • Role of Co-Sensitizers in Dye-Sensitized Solar Cells
  • Role of Co‐Sensitizers in Dye‐Sensitized Solar Cells

    Better together: Co-sensitizers are important additives that reduce charge recombination and aggregation processes in dye-sensitized solar cells, improving the power conversion efficiency and stability of devices. Various co-sensitizers are incorporated in devices implementing both Ru- and porphyrin-based dyes, leading to remarkable power conversion efficiency values and demonstrating their role towards improved device performance.

    [Minireview]
    Narra Vamsi Krishna, Jonnadula Venkata Suman Krishna, Madoori Mrinalini, Seelam Prasanthkumar, Lingamallu Giribabu
    ChemSusChem, November 24, 2017, https://doi.org/10.1002/cssc.201701224 Read article



  • Benzoic Acid-Promoted Intermolecular [3+2] Cycloaddition with Air as the Terminal Oxidant: General Approach toward Pyrrolo[2, 1-a]isoquinolines
  • Benzoic Acid‐Promoted Intermolecular [3+2] Cycloaddition with Air as the Terminal Oxidant: General Approach toward Pyrrolo[2, 1‐a]isoquinolines

    In this manuscript, we developed a benzoic acid mediated intermolecular 1,3-dipolar addition for the construction of pyrrolo[2, 1-a]isoquinoline derivatives via capturing the azomethine ylides generated in situ from 1,2,3,4-tetrahydroisoquinoline (THIQ) and arylglyoxal monohydrates. This metal-free protocol utilizes air as the terminal oxidant, which provides a green and atom economic access to pyrrolo[2, 1-a]isoquinolines in high yields under mild conditions.

    [Communication]
    Kailu Zheng, Shiyi Zhuang, Minqi You, Wenming Shu, Anxin Wu, Yandong Wu
    ChemistrySelect, November 24, 2017, https://doi.org/10.1002/slct.201702044 Read article



  • Catalytic Oxidation of Biosourced 3-Methylphtalic Anhydride under O2: One-Pot Hemimellitic Acid Synthesis and Novel Example of Biomass Valorization.
  • Catalytic Oxidation of Biosourced 3‐Methylphtalic Anhydride under O2: One‐Pot Hemimellitic Acid Synthesis and Novel Example of Biomass Valorization.

    100% biosourced 3-methylphtalic anhydride, formed by cycloaddition of precursors obtained from furfural, was converted to benzene-1,2,3-tricarboxylic acid (hemimellitic acid) in good yield by one-pot tandem oxidation/hydrolysis catalyzed by Co/Mn/Br catalytic system in AcOH under pressurised air. The use of an anhydride functional group as masked vicinal dicarboxylic groups allowed to prevent possible risk of catalyst deactivation known to occur upon coordination of metal species in similar systems.

    [Communication]
    Pascal D. Giorgi, Siu-Ha Soo-Tang, Sylvain Antoniotti, Jan C. van der Waal
    ChemistrySelect, November 24, 2017, https://doi.org/10.1002/slct.201702274 Read article



  • Graphene-Polymer//Graphene-Manganese Oxide Nanocomposites-Based Asymmetric High Energy Supercapacitor with 1.8 V Cell Voltage in Aqueous Solution
  • Graphene‐Polymer//Graphene‐Manganese Oxide Nanocomposites‐Based Asymmetric High Energy Supercapacitor with 1.8 V Cell Voltage in Aqueous Solution

    Asymmetric supercapacitor with a cell voltage of 1.8 V was fabricated using RGO-PEDOT.PSS and RGO-CNF-MnO2 as negative and positive electrodes in aqueous 1 M Na2SO4 solution, respectively. It showed a high energy density of 21 Wh/Kg and excellent capacitance retention of 96% after 20000 cycles.

    [Full Paper]
    Balasubramanian Amutha, Kaipannan Subramani, Pula Nagesh Reddy, Marappan Sathish
    ChemistrySelect, November 24, 2017, https://doi.org/10.1002/slct.201701979 Read article



  • Complete Depolymerization and Repolymerization of a Sugar Poly(orthoester)
  • Complete Depolymerization and Repolymerization of a Sugar Poly(orthoester)

    Candy wrapper: Herein, a sugar poly(orthoester) is shown to be completely and reversibly depolymerized under acidic conditions. Instead of the original monomer, the depolymerization gave stable cyclic product 1,6-anhydro glucopyranose in most cases. However, this pathway could be inhibited by chemically deactivating a key intermediate and thus favoring the formation of the original monomer. Efficient repolymerizaton of the regenerated monomer is also demonstrated.

    [Communication]
    Lingyao Li, Sampa Maiti, Nicole A. Thompson, Ian J. Milligan, Wenjun Du
    ChemSusChem, November 24, 2017, https://doi.org/10.1002/cssc.201701870 Read article



  • New Hybrid Nanomaterials Derived from Chemical Functionalization of Clicked Graphene Oxide / Magnetite Nanocomposite with Peroxopolyoxotungstate Species
  • New Hybrid Nanomaterials Derived from Chemical Functionalization of Clicked Graphene Oxide / Magnetite Nanocomposite with Peroxopolyoxotungstate Species

    Two new hybrid nanomaterials were developed by immobilization of peroxopolyoxotungstate on the surface of clicked graphene oxide/magnetite nanocomposite. Catalytic investigation of the prepared hybrid nanomaterials showed their high activities and selectivities (>99%) in the epoxidation of olefins with H2O2 under mild reaction conditions. In addition, they can be magnetically separated and reused several times without remarkable loss of catalytic efficiency.

    [Full Paper]
    Majid Masteri-Farahani, Maryam Modarres
    ChemistrySelect, November 24, 2017, https://doi.org/10.1002/slct.201701690 Read article



  • Microwave-Assisted Highly Efficient Route to 4-Aminoquinoline-Phthalimide Conjugates: Synthesis and Anti-Tubercular Evaluation
  • Microwave‐Assisted Highly Efficient Route to 4‐Aminoquinoline‐Phthalimide Conjugates: Synthesis and Anti‐Tubercular Evaluation

    Synthesis of 4-aminoquinoline-phthalimides was attempted under both conventional and microwave heating. Best results in terms of reactions yields were obtained by microwave heating in DMSO at 160 ΟC for two minutes. The synthesized compounds were evaluated for their anti-TB and cytotoxic activities. The scaffolds exhibited MIC99 values ranging from 13.7–692.3 μM against mc26230 strain of M. tuberculosis with low to moderate cytotoxicity against J774 murine macrophage cell line.

    [Communication]
    Anu Rani, Albertus Viljoen, Sumanjit, Laurent Kremer, Vipan Kumar
    ChemistrySelect, November 24, 2017, https://doi.org/10.1002/slct.201702220 Read article



  • WtF-Nano: One-Pot Dewatering and Water-Free Topochemical Modification of Nanocellulose in Ionic Liquids or γ-Valerolactone
  • WtF‐Nano: One‐Pot Dewatering and Water‐Free Topochemical Modification of Nanocellulose in Ionic Liquids or γ‐Valerolactone

    Down by dewater: Stabilization of nanofibrillar cellulose during evaporative dewatering is facilitated by using non-dissolving additive ionic liquids. This enables highly efficient water-free topochemical modification (a process denoted as WtF-Nano), yielding highly dispersed modified nanocelluloses.

    [Full Paper]
    Tiina Laaksonen, Jussi K. J. Helminen, Laura Lemetti, Jesper Långbacka, Daniel Rico del Cerro, Michael Hummel, Ilari Filpponen, Antti H. Rantamäki, Tia Kakko, Marianna L. Kemell, Susanne K. Wiedmer, Sami Heikkinen, Ilkka Kilpeläinen, Alistair W. T. King
    ChemSusChem, November 24, 2017, https://doi.org/10.1002/cssc.201701344 Read article



  • Design, Synthesis, Biological Evaluation, and X-ray Studies of HIV-1 Protease Inhibitors with Modified P2′ Ligands of Darunavir
  • Design, Synthesis, Biological Evaluation, and X‐ray Studies of HIV‐1 Protease Inhibitors with Modified P2′ Ligands of Darunavir

    Structured antivirals: We report the structure-based design, synthesis, biological evaluation, and X-ray structural studies of a series of highly potent HIV-1 protease inhibitors containing novel P2′ ligands to interact with protease active site residues. The inhibitors were designed to enhance backbone binding interactions, particularly at the S2′ subsite. A number of inhibitors displayed very potent enzyme inhibitory and antiviral activity and remained quite potent against darunavir-resistant HIV-1 variants. X-ray crystallographic work revealed key interactions in the S2′ subsite.

    [Full Paper]
    Arun K. Ghosh, W. Sean Fyvie, Margherita Brindisi, Melinda Steffey, Johnson Agniswamy, Yuan-Fang Wang, Manabu Aoki, Masayuki Amano, Irene T. Weber, Hiroaki Mitsuya
    ChemMedChem, November 24, 2017, https://doi.org/10.1002/cmdc.201700614 Read article



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